ABSTRACT
Antimicrobial
therapeutic strategies
widely referred
to as the Keyes
Technique were
directed at suppression
of the periodontopathic
microflora of
7 juvenile periodontitis
patients who
were treated and
followed for at least
22 months.
Following collection
of baseline clinical
and microbiological
parameters, the
patients received
meticulous scaling
and root planing
of all teeth with
concomitant irrigation
to probing depth
of saturated inorganic
salt solutions
and 1% chloramine-T.
The patients were
recalled at approximately
2- to 3-month intervals
for maintenance
care which was
modulated by clinical
parameters and
phase-contrast
microscopic findings.
Six patients received
at least 2 courses
of systemic tetracycline
(1 gm/day for 14
days) during the
study. Patient
home treatments
included daily
application of
a sodium bicarbonate/3%
hydrogen peroxide
paste, and inorganic
salt irrigations. Clinical reevaluations
made an average
of 29.6 months
posttreatment showed
statistically significant
(P<.01) decreases
in bleeding on
probing in all
patients. Significant
decreases in probing
depth, and gains
in clinical attachment
levels also were
found in all patients,
particularly in
advanced sites
initially 4 to
6 mm and >7
mm in probing depth.
Among sites with
initial attachment
loss >5 mm,
25.8% experienced
a >3 mm gain
in clinical attachment
level from baseline
with therapy. Significant
decreases in motile
organisms and crevicular
polymorphonuclear
leukocytes present
in the subgingival
plaque of the patients
also occurred with
the antimicrobial
therapy employed. These findings
demonstrate that
juvenile periodontitis
patients can be
treated successfully
and maintained
on a long-term
basis without periodontal
surgery when appropriate
antimicrobial therapy
is directed at
the subgingival
periodontopathic
microbiota. (Pediatr
Dent. 1985;7:259-270)
Source:
http://www.aapd.org/searcharticles/article.asp?ARTICLE_ID=1452
|